2004.03.23 22:54 "Re: [Tiff] TIFF format 16 bit gray scale", by Bob Friesenhahn
TIFF 6.0 only goes up to 8 bit gray scale. But there seems to be a 16 bit version, and also a 48 bit color version (16 bits each of red, green, and blue), used by things like the UMAX 2100 XL scanner with SilverFast Ai software (www.umax.com). If there a version of libtiff available that can read those image files?
Libtiff can handle 16 bit gray scale (or even 15 bit gray scale, cough!), but it leaves actual parsing/unpacking of the strip data to the API user. See development GraphicsMagick (http://www.graphicsmagick.org/) for an example of how to do this.